Short-term impact of tirzepatide on metabolic hypogonadism and body composition in patients with obesity: a controlled pilot study

Short-term impact of tirzepatide on metabolic hypogonadism and body composition in patients with obesity: a controlled pilot study

Abstract Background Tirzepatide (TZP), a dual agonist of glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, has recently been introduced in Italy for the treatment of obesity. Obesity is frequently associated with metabolic hypogonadism, which is characteri...

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Bibliographic Details
Main Authors: Sandro La Vignera, Rossella Cannarella, Vincenzo Garofalo, Andrea Crafa, Federica Barbagallo, Rosita A. Condorelli, Aldo E. Calogero
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Reproductive Biology and Endocrinology
Subjects:
Tirzepatide
Metabolic hypogonadism
Testosterone
Body composition
Fat mass
Gonadotropins
Online Access:https://doi.org/10.1186/s12958-025-01425-9
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https://doi.org/10.1186/s12958-025-01425-9

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