Connection between circulating inflammatory cytokines and non-small cell lung cancer: integrated Mendelian randomization and gene function analysis

Connection between circulating inflammatory cytokines and non-small cell lung cancer: integrated Mendelian randomization and gene function analysis

Abstract Background A lot of cancers including non-small cell lung cancer (NSCLC) arise in association with chronic inflammation. In this study, Mendelian randomization (MR) and gene function analyses were integrated to address the connection between circulating inflammatory cytokines and NSCLC, and...

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Main Authors: Ke Niu, Jing Tang, Jianxin Zhong, Lin Zheng, Yayu Zhu, Huijuan Ling, Yu Liu, Qing Xu, Ping Qiu, Liwen Chen
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
Subjects:
Circulating inflammatory cytokines
Blood metabolites
Non-small cell lung cancer
Mendelian randomization
Gene function analysis
Online Access:https://doi.org/10.1007/s12672-025-02817-4
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https://doi.org/10.1007/s12672-025-02817-4

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