d-Amino acids differentially trigger an inflammatory environment in vitro

d-Amino acids differentially trigger an inflammatory environment in vitro

Abstract Studies in vivo have demonstrated that the accumulation of d-amino acids (d-AAs) is associated with age-related diseases and increased immune activation. However, the underlying mechanism(s) of these observations are not well defined. The metabolism of d-AAs by d-amino oxidase (DAO) produce...

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Bibliographic Details
Main Authors: Siew Hwei Yap, Cheng Siang Lee, Nur Diyana Zulkifli, Darshinie Suresh, Kenji Hamase, Kumitaa Theva Das, Reena Rajasuriar, Kok Hoong Leong
Format: Article
Language:English
Published: Springer 2024-02-01
Series:Amino Acids
Subjects:
d-Amino acid oxidase
d-Serine
d-Alanine
Inflammation
TNF-α
Online Access:https://doi.org/10.1007/s00726-023-03360-8
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https://doi.org/10.1007/s00726-023-03360-8

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