Memantine augmentation of escitalopram in treatment of executive function among patients with obsessive-compulsive disorder (OCD): a double-blind placebo-controlled randomized clinical trial

Memantine augmentation of escitalopram in treatment of executive function among patients with obsessive-compulsive disorder (OCD): a double-blind placebo-controlled randomized clinical trial

Abstract Background Obsessive-Compulsive Disorder (OCD) involves persistent, intrusive thoughts and repetitive behaviors. While SSRIs like escitalopram are common treatments, some patients do not respond adequately. This study aims to assess memantine’s effectiveness as an adjunct therapy to enhance...

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Bibliographic Details
Main Authors: Hasan Mirzazadeh, Younes Ghaeminia, Amin Mohamad Niaei, Mohammadsadegh Kamran, Leila Razeghian Jahromi, Reza Moshfeghinia
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Psychiatry
Subjects:
Memantine
Escitalopram
Obsessive-Compulsive Disorder (OCD)
Executive function
Augmentation therapy
Online Access:https://doi.org/10.1186/s12888-025-06856-7
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https://doi.org/10.1186/s12888-025-06856-7

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