Exposure of lung fibroblasts to PM2.5 and lead (Pb) induces fibrosis and apoptosis in alveolar epithelial cells via a paracrine effect

Exposure of lung fibroblasts to PM2.5 and lead (Pb) induces fibrosis and apoptosis in alveolar epithelial cells via a paracrine effect

Exposure to fine particulate matter (PM2.5) and heavy metals (HMs) in the air is closely associated with the incidence and exacerbation of pulmonary fibrosis. Although the specific responses of alveolar epithelial cells (AECs) and lung fibroblasts to PM2.5 or HM exposure have been well defined, the...

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Bibliographic Details
Main Authors: Jung-Yun Choi, Minje Kang, Ji-Hye Jung, Woo Jin Kim, Hyo-Seon Yang, Kyuhong Lee, Jooyeon Lee, Se-Ran Yang, Chin Kook Rhee, Seok-Ho Hong
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Particulate matter
Lead
Fibrosis
Apoptosis
Lung fibroblasts
Alveolar epithelial cells
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324014775
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