Dietary silymarin supplementation enhances chemotherapy efficacy of capecitabine and irinotecan and mitigates hepatotoxicity in a mouse model of colon cancer

Background and purpose: The flavonoid silymarin (SMN) has shown promise due to its antioxidant, anti-inflammatory, and anticancer properties. SMN has been widely used in preclinical and clinical studies to treat various types of cancer, alone and with chemotherapy agents. Recent research suggests th...

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Bibliographic Details
Main Authors: Sepideh Hassani, Hassan Malekinejad, Mohammad Hassan Khadem-Ansari, Ata Abbasi, Fatemeh Kheradmand
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
Online Access:https://journals.lww.com/10.4103/RPS.RPS_204_24
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