Sequential structure probing of cotranscriptional RNA folding intermediates

Abstract Cotranscriptional RNA folding pathways typically involve the sequential formation of folding intermediates. Existing methods for cotranscriptional RNA structure probing map the structure of nascent RNA in the context of a terminally arrested transcription elongation complex. Consequently, t...

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Bibliographic Details
Main Authors: Courtney E. Szyjka, Skyler L. Kelly, Eric J. Strobel
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60425-w
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