Prenatal linuron exposure disrupts adrenal steroidogenesis and induces adrenal insufficiency in male rat offspring

Prenatal linuron exposure disrupts adrenal steroidogenesis and induces adrenal insufficiency in male rat offspring

Linuron, a commonly used agricultural herbicide in certain regions, has raised concerns due to its endocrine toxicity in humans and wildlife. While its gonadal toxicity is established, its direct impact on prenatal adrenal development remains unexplored. Pregnant Sprague-Dawley rats received linuron...

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Bibliographic Details
Main Authors: Duoduo Quan, Yang Cheng, Xinhe Zhou, Jiao Xu, Tingting Shangguan, Yibing Tang, Zhiguang Zhao, Qiang Xu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Research in Toxicology
Subjects:
Linuron
Herbicide
Adrenal development
Steroidogenesis
Antioxidants
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X25000404
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