Characterization of the procoagulant phenotype of amniotic fluid across gestation in rhesus macaques and humans

Characterization of the procoagulant phenotype of amniotic fluid across gestation in rhesus macaques and humans

Background: Amniotic fluid (AF) plays a key role in fetal development, yet the evolving composition of AF and its effects on hemostasis and thrombosis are poorly understood. Objectives: To characterize the procoagulant properties of AF as a function of gestation in humans and nonhuman primates. Meth...

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Main Authors: Chih Jen Yang, Lyndsey E. Shorey-Kendrick, Cristina Puy, Ashley E. Benson, Phillip A. Wilmarth, Ashok P. Reddy, Keith D. Zientek, Kilsun Kim, Adam Crosland, Chaevien S. Clendinen, Lisa M. Bramer, Olivia L. Hagen, Helen H. Vu, Joseph E. Aslan, Owen J.T. McCarty, Joseph J. Shatzel, Brian P. Scottoline, Jamie O. Lo
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
amniotic fluid
coagulation factors
hemostasis
pregnancy
rhesus macaque
Online Access:http://www.sciencedirect.com/science/article/pii/S2475037924003716
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