The Connection Between Oxidative Stress, Mitochondrial Dysfunction, Iron Metabolism and Microglia in Multiple Sclerosis: A Narrative Review

The Connection Between Oxidative Stress, Mitochondrial Dysfunction, Iron Metabolism and Microglia in Multiple Sclerosis: A Narrative Review

In recent years, in the pathogenesis of multiple sclerosis, emphasis has been placed on mitochondrial processes that influence the onset of the disease. Oxidative stress would be one of the consequences of mitochondrial dysfunction, and its impact on brain tissue is well described. Microglia, as a b...

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Bibliographic Details
Main Authors: Simonida Delic, Svetlana Miletic Drakulic, Milos Stepovic, Jovana Milosavljevic, Marija Kovacevic Dimitrijevic, Kristijan Jovanovic, Ivona Marinkovic, Melanija Tepavcevic, Nikoleta Janicijevic, Aleksandra Mitrovic, Danica Igrutinovic, Maja Vulovic
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:NeuroSci
Subjects:
multiple sclerosis
microglia
oxidative stress
mitochondrial dysfunction
iron deposition
Online Access:https://www.mdpi.com/2673-4087/6/1/23
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