Nafamostat mesylate augments survival in rats afflicted by exertional heat stroke

Nafamostat mesylate augments survival in rats afflicted by exertional heat stroke

ObjectiveTo evaluate the impact of Nafamostat mesylate (NM) in improving survival outcomes among rats subjected to exertional heat stroke.MethodsThis study involved a cohort of 45 specific pathogen-free (SPF) male Sprague Dawley (SD) rats. After successfully inducing exertional heat stroke, the rats...

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Bibliographic Details
Main Authors: Qingwei Lin, Zhuqing Luo, Longping He, Lincui Zhong, Qingbo Zeng, Ye Zhou, Qi Chen, Xingping Deng, Xiaomin Song, Qing Song, Jingchun Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
nafamostat mesylate
rats
heatstroke
proteomics
thrombosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1559181/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1559181/full

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