Deciphering lung granulomas in HIV & TB co-infection: unveiling macrophages aggregation with IL6R/STAT3 activation

Deciphering lung granulomas in HIV & TB co-infection: unveiling macrophages aggregation with IL6R/STAT3 activation

Tuberculosis (TB) remains a leading cause of mortality among individuals coinfected with HIV, characterized by progressive pulmonary inflammation. Despite TB’s hallmark being focal granulomatous lung lesions, our understanding of the histopathological features and regulation of inflammation in HIV &...

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Bibliographic Details
Main Authors: Qian Li, Cheng Wang, Jizhou Gou, Simo Kitanovski, XiangYi Tang, Yixuan Cai, Chenxia Zhang, Xiling Zhang, Zhenfeng Zhang, Yuanwang Qiu, Fang Zhao, Mengji Lu, Yun He, Jun Wang, Hongzhou Lu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
Macrophage
human immunodeficiency virus
Mycobacterium tuberculosis
multiplex staining
spatial transcriptomics
IL-6R/STAT3 pathway
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2366359
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https://www.tandfonline.com/doi/10.1080/22221751.2024.2366359

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