Loss of tricellular tight junction tricellulin leads to hyposalivation in Sjögren’s syndrome

Abstract Tricellulin, a key tricellular tight junction (TJ) protein, is essential for maintaining the barrier integrity of acinar epithelia against macromolecular passage in salivary glands. This study aims to explore the role and regulatory mechanism of tricellulin in the development of salivary gl...

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Bibliographic Details
Main Authors: Xiangdi Mao, Haibing Li, Sainan Min, Jiazeng Su, Pan Wei, Yan Zhang, Qihua He, Liling Wu, Guangyan Yu, Xin Cong
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-025-00349-9
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