Immunomodulation by extracorporeal ozone-based bactericide system in porcine Pseudomonas aeruginosa septic shock

Immunomodulation by extracorporeal ozone-based bactericide system in porcine Pseudomonas aeruginosa septic shock

Abstract Sepsis is associated with substantial mortality rates. Traditional treatment strategies often fail to address the underlying dysregulation in immune response, necessitating novel therapeutic approaches. Ozone (O3) is an inorganic molecule with no evident function in the body. We investigate...

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Bibliographic Details
Main Authors: Henrik Rundgren, Johan Sjöholm, Sanja Juric, Pellina Janson, Joline Kolerud, Robert Wallin, Paul Skorup, Miklos Lipcsey, Mattias Günther
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Porcine sepsis model
Ozone
Pseudomonas aeruginosa
Antibiotic resistance
Intensive care
Online Access:https://doi.org/10.1038/s41598-025-07408-5
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https://doi.org/10.1038/s41598-025-07408-5

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