Novel compound heterozygous DOCK6 variants expand the mutational spectrum in prenatal diagnosis of Adams-Oliver syndrome 2

Abstract Background Adams-Oliver syndrome (AOS) is a rare developmental disorder, and the DOCK6 gene is an identified AOS gene. This report highlights the prenatal diagnosis of AOS-2 by ultrasonography and genetic testing. Methods A growth-restricted fetus with bilateral ventriculomegaly, paraventri...

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Bibliographic Details
Main Authors: Xue Zhong, Xuan Zheng, Yinglei Xv, Kangxi Cai, Qianqian Wang, Shiguo Liu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Medical Genomics
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Online Access:https://doi.org/10.1186/s12920-025-02157-w
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