A Plasmodium late liver stage arresting GAP provides superior protection in mice

Abstract Liver-stage genetically attenuated malaria parasites (GAPs) are powerful immunogens that provide protection against sporozoite challenge. We previously generated two late liver-stage-arresting GAPs by deleting the stearoyl-CoA desaturase (Scd) or sporozoite conserved orthologous transcript...

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Bibliographic Details
Main Authors: Akancha Mishra, Plabita Paul, Mrigank Srivastava, Satish Mishra
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-00975-0
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