Decoding aging in the heart via single cell dual omics of non-cardiomyocytes

Summary: To understand heart aging at the single-cell level, we employed single-cell dual omics (scRNA-seq and scATAC-seq) in profiling non-myocytes (non-CMs) from young, middle-aged, and elderly mice. Non-CMs, vital in heart development, physiology, and pathology, are understudied compared to cardi...

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Bibliographic Details
Main Authors: Yiran Song, Li Wang, Haofei Wang, Hong Ma, Jun Xu, Jiandong Liu, Li Qian
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224026968
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