Cyclosporine and Herbal Supplement Interactions
Cyclosporine (CyA) is a well-known immunosuppressant with a narrow therapeutic window. Its bioavailability is affected by many other traditional drugs and herbal extracts. Cytochrome P-450 isoenzymes CYP3A4 and CYP3A5 and protein P-glycoprotein (P-gp) are involved in CyA bioavailability. Interaction...
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Main Authors: | D. Colombo, L. Lunardon, G. Bellia |
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Format: | Article |
Language: | English |
Published: |
Wiley
2014-01-01
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Series: | Journal of Toxicology |
Online Access: | http://dx.doi.org/10.1155/2014/145325 |
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