TBL2 Promotes Tumorigenesis via PRMT5/WDR77‐Mediated AKT Activation in Breast Cancer

TBL2 Promotes Tumorigenesis via PRMT5/WDR77‐Mediated AKT Activation in Breast Cancer

Abstract Breast cancer (BC) is a common malignancy that affects women worldwide. Although transducing beta‐like 2 (TBL2), a member of the WD40 repeat protein family, has been implicated in various intracellular signaling pathways, its precise function in BC remains unclear. The expression of TBL2 is...

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Bibliographic Details
Main Authors: Xiuqing Lu, Chao Zhang, Lewei Zhu, Sifen Wang, Lijun Zeng, Wenjing Zhong, Xuxia Wu, Qi Yuan, Hailin Tang, Shien Cui, Yeru Tan, Yuehua Li, Weidong Wei
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Advanced Science
Subjects:
AKT phosphorylation
breast cancer
PRMT5/WDR77
proliferation
TBL2
Online Access:https://doi.org/10.1002/advs.202400160
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https://doi.org/10.1002/advs.202400160

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