Application of single-cell and spatial omics in deciphering cellular hallmarks of cancer drug response and resistance

Abstract Drug resistance poses a significant challenge in cancer therapy, contributing to rapid recurrence, disease progression, and high patient mortality. Despite its critical impact, few reliable predictors for cancer drug response or failure have been established for clinical application. Tumor...

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Bibliographic Details
Main Authors: Xiaoxia Cheng, Ting Peng, Tian Chu, Yiqun Yang, Jia Liu, Qinglei Gao, Canhui Cao, Juncheng Wei
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Hematology & Oncology
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Online Access:https://doi.org/10.1186/s13045-025-01722-1
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