Identification of the disulfidptosis-related key gene CD2AP as a potential biomarker and new therapeutic target for LUAD patients by comprehensive multi-omics analysis

Identification of the disulfidptosis-related key gene CD2AP as a potential biomarker and new therapeutic target for LUAD patients by comprehensive multi-omics analysis

Abstract Background Lung Adenocarcinoma (LUAD) is a major subtype of Non-Small Cell Lung Cancer (NSCLC) with poor prognosis. Despite advances in molecular targeted therapy and immunotherapy, the five-year survival rate remains low. Disulfidptosis, a novel cell death mechanism, may play a role in tum...

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Bibliographic Details
Main Authors: Zhiwu Lin, Jing Lv, Chuanqiang Dai, Yuanwei Zhai, Jiudong Jiang, Yang Gao, Rulin Li, Jiangang Fan, Yang Yu, Liang Wu, Yanchun Yang
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Discover Oncology
Subjects:
CD2AP
Disulfidptosis
LUAD
Multi-omics
Therapeutic target
Programmed cell death
Online Access:https://doi.org/10.1007/s12672-025-02308-6
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https://doi.org/10.1007/s12672-025-02308-6

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