NMDA receptor antagonists mitigate COVID-19-induced neuroinflammation and improve survival in a mouse model

NMDA receptor antagonists mitigate COVID-19-induced neuroinflammation and improve survival in a mouse model

Abstract The virus known to cause COVID-19, SARS-CoV-2, exhibits severe and complex neurological symptoms. These effects may be attributed to a virus-induced neuroinflammatory environment, warranting exploration of the respiratory centers of the brain, namely the pons and medulla, specifically in re...

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Main Authors: Emily R. Prantzalos, Jane P. Chesser, Judy Songrady Logan, Kristen A. McLaurin, Charles D. Anderson, Jon D. Gabbard, William E. Severson, Kenneth E. Palmer, Bobbi Jo Mullins, Linda Dwoskin, Jill R. Turner
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-00738-4
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https://doi.org/10.1038/s41598-025-00738-4

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