Associations between arterial stiffening and brain structure, perfusion, and cognition in the Whitehall II Imaging Sub-study: A retrospective cohort study.

Associations between arterial stiffening and brain structure, perfusion, and cognition in the Whitehall II Imaging Sub-study: A retrospective cohort study.

<h4>Background</h4>Aortic stiffness is closely linked with cardiovascular diseases (CVDs), but recent studies suggest that it is also a risk factor for cognitive decline and dementia. However, the brain changes underlying this risk are unclear. We examined whether aortic stiffening durin...

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Main Authors: Sana Suri, Scott T Chiesa, Enikő Zsoldos, Clare E Mackay, Nicola Filippini, Ludovica Griffanti, Abda Mahmood, Archana Singh-Manoux, Martin J Shipley, Eric J Brunner, Mika Kivimäki, John E Deanfield, Klaus P Ebmeier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-12-01
Series:PLoS Medicine
Online Access:https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1003467&type=printable
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https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1003467&type=printable

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