Radiation-induced exosomal miR-21 enhances tumor proliferation and invasiveness in breast cancer: implications for poor prognosis in radiotherapy patients

Radiation-induced exosomal miR-21 enhances tumor proliferation and invasiveness in breast cancer: implications for poor prognosis in radiotherapy patients

Abstract Radiotherapy is widely used as an effective non-surgical strategy to control malignant tumors. However, recurrence is one of common causes of treatment failure even after the effective radiotherapy. In this study, we focused on the effects of radiation-induced exosomal miR-21 on the tumor m...

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Main Authors: Kyungmin Kim, Kyung Oh Jung, Sera Oh, Young-Hwa Kim, Seok-Yong Lee, Seongje Hong, Su Han Cho, Hyejin Kim, Siyeon Rhee, Gi Jeong Cheon, Keon Wook Kang, June-Key Chung, Hyewon Youn
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Experimental Hematology & Oncology
Subjects:
Radiotherapy
Radiation-induced exosomes
Exosomal miR-21
Poor prognosis of breast cancer patients
Online Access:https://doi.org/10.1186/s40164-024-00585-5
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https://doi.org/10.1186/s40164-024-00585-5

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