A computational study to identify potential inhibitors targeting the TKB domain of CBL-B
Abstract CBL-B is an E3-ubiquitin ligase that serves a key role in modulating immune response by negatively inhibiting effector T-cell activation. Inhibitors of CBL-B would be an effective way for immune activation, making it a promising target for cancer immunotherapy and other related immune disea...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-04-01
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| Series: | Discover Chemistry |
| Online Access: | https://doi.org/10.1007/s44371-025-00153-8 |
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