TIA1‐Mediated Stress Granules Promote the Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis through Upregulating IL‐31RA Signaling

TIA1‐Mediated Stress Granules Promote the Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis through Upregulating IL‐31RA Signaling

Abstract The dysfunction of stress granules (SGs) plays a crucial role in the pathogenesis of various neurological disorders, with T cell intracellular antigen 1 (TIA1) being a key component of SGs. However, the role and mechanism of TIA1‐mediated SGs in experimental autoimmune encephalomyelitis (EA...

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Main Authors: Xin Hua, Lingting Jin, Zheyu Fang, Yiyun Weng, Yuan Zhang, Jingjing Zhang, Dewei Xie, Yang Tang, Siyu Guo, Yingying Huang, Yilin Dai, Jia Li, Zhihui Huang, Xu Zhang
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
experimental autoimmune encephalomyelitis
multiple sclerosis
neuroinflammation
stress granules
T‐cell intracellular antigen 1
Online Access:https://doi.org/10.1002/advs.202409086
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https://doi.org/10.1002/advs.202409086

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