Elevated interleukin-8 expression by skin fibroblasts as a potential contributor to pain in women with Fabry disease.

Elevated interleukin-8 expression by skin fibroblasts as a potential contributor to pain in women with Fabry disease.

Fabry disease (FD) is a lysosomal storage disorder of X-linked inheritance. Mutations in the α-galactosidase A gene lead to cellular globotriaosylceramide (Gb3) depositions and triggerable acral burning pain in both sexes as an early FD symptom of unknown pathophysiology. We aimed at elucidating the...

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Bibliographic Details
Main Authors: Lukas Hofmann, Julia Grüner, Katharina Klug, Maximilian Breyer, Thomas Klein, Vanessa Hochheimer, Laura Wagenhäuser, Erhard Wischmeyer, Nurcan Üçeyler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0300687&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0300687&type=printable

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