Clostridium butyricum ameliorates indomethacin-induced enteropathy by promoting MUC2 secretion via suppressing the Notch pathway

Clostridium butyricum ameliorates indomethacin-induced enteropathy by promoting MUC2 secretion via suppressing the Notch pathway

Nonsteroidal anti-inflammatory drug (NSAID) enteropathy is a serious clinical complication with no effective treatments available. Modulating the intestinal microbiota through dietary and nutritional targets is a promising strategy for preventing NSAID enteropathy. This study aimed to investigate th...

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Bibliographic Details
Main Authors: Lanping Zhu, Yang Luo, Yaxin Liu, Siyuan Sun, Junjie Yuan, Lijun Zhang, Weilong Zhong, Shuang Ma, Zihan Yu, Jinjie Zhou, Xin Chen, Jingwen Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Microbiology
Subjects:
small intestinal damage
non-steroidal anti-inflammatory drugs
Clostridium butyricum
Notch pathway
mucin MUC2
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1509876/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1509876/full

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