Ancient and novel small RNA pathways compensate for the loss of piRNAs in multiple independent nematode lineages.

Ancient and novel small RNA pathways compensate for the loss of piRNAs in multiple independent nematode lineages.

Small RNA pathways act at the front line of defence against transposable elements across the Eukaryota. In animals, Piwi interacting small RNAs (piRNAs) are a crucial arm of this defence. However, the evolutionary relationships among piRNAs and other small RNA pathways targeting transposable element...

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Main Authors: Peter Sarkies, Murray E Selkirk, John T Jones, Vivian Blok, Thomas Boothby, Bob Goldstein, Ben Hanelt, Alex Ardila-Garcia, Naomi M Fast, Phillip M Schiffer, Christopher Kraus, Mark J Taylor, Georgios Koutsovoulos, Mark L Blaxter, Eric A Miska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.1002061
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https://doi.org/10.1371/journal.pbio.1002061

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