COVID-19 patient serum-derived extracellular vesicles deliver miR-20b-5p induces neutrophil extracellular traps

COVID-19 patient serum-derived extracellular vesicles deliver miR-20b-5p induces neutrophil extracellular traps

Abstract Background Severe cases of COVID-19 are characterized by an excessive presence of neutrophils. Neutrophil extracellular traps (NETs), released by activated neutrophils due to SARS-CoV-2 infection, contribute to lung epithelial cell death and are key drivers in COVID-19-associated immunothro...

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Main Authors: Yao Liao, Yuheng Liu, Dinghao Li, Shiqi Luo, Yun Huang, Junwei Wu, Jin Su, Yi Yang, Ji Wu, Zifeng Zhu, Mengxi Yanglan, Haiyi Deng, Xinyi Wu, Junhao Xu, Feiyang Cao, Chunmei Cai, Zhen Li, Ruibing Yang, Xiaoyan Deng, Jie Wei, Lifu Wang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Cell Communication and Signaling
Subjects:
COVID-19
Extracellular vesicles
Neutrophil extracellular traps
miRNAs
miR-20b-5p
Online Access:https://doi.org/10.1186/s12964-025-02095-1
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https://doi.org/10.1186/s12964-025-02095-1

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