Performance of a six-methylation-marker assay in predicting LEEP specimen histology results of cervical HSIL patients: a retrospective study

Performance of a six-methylation-marker assay in predicting LEEP specimen histology results of cervical HSIL patients: a retrospective study

Abstract Background Discrepancies have been found between preoperative colposcopic biopsy results and histology results of loop electrical excision procedure (LEEP) specimens. GynTect® is a six-methylation-marker assay that has demonstrated its potential as a triage tool for cervical lesion detectio...

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Bibliographic Details
Main Authors: Ruolan Wu, Yingting Wei, Anyue Wu, Jinhua Huang, Ruiju He, Liying Gu, Zubei Hong, Lihua Qiu
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cancer
Subjects:
Cervical cancer
DNA methylation
Human papillomavirus
LEEP
Pathology
Online Access:https://doi.org/10.1186/s12885-025-13671-6
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https://doi.org/10.1186/s12885-025-13671-6

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