Cannabidiol Modulates Neuroinflammatory and Estrogen-Related Pathways in a Sex-Specific Manner in a Chronic Stress Model of Depression

Evidence indicates a bidirectional link between depressive symptoms and neuroinflammation. This study evaluated chronic cannabidiol (CBD) treatment effects in male and female rats subjected to the unpredictable chronic mild stress (UCMS) model of depression. We analyzed the gene expression related t...

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Bibliographic Details
Main Authors: Uri Bright, Irit Akirav
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/2/99
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