Whole-exome sequencing analysis identifies risk genes for schizophrenia

Abstract Rare coding variants across many genes contribute to schizophrenia liability, but they have only been implicated in 12 genes at exome-wide levels of significance. To increase power for gene discovery, we analyse exome-sequencing data for rare coding variants in a new sample of 4650 schizoph...

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Bibliographic Details
Main Authors: Sophie L. Chick, Peter Holmans, Darren Cameron, Detelina Grozeva, Rebecca Sims, Julie Williams, Nicholas J. Bray, Michael J. Owen, Michael C. O’Donovan, James T. R. Walters, Elliott Rees
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62429-y
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