Synergizing sono-piezo with exosome suppression using doping-engineered hydroxyapatite for potentiated tumor treatment through immunoactivation

Synergizing sono-piezo with exosome suppression using doping-engineered hydroxyapatite for potentiated tumor treatment through immunoactivation

Abstract Piezoelectric nanomaterials that generate reactive oxygen species (ROS) through piezoelectric polarization under mechanical stimulation have emerged as a promising cancer therapy platform. However, their potential is limited by poor piezoresponse, low catalytic efficiency, and the exacerbat...

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Bibliographic Details
Main Authors: Xinran Qu, Qin Fan, Yingying Liu, Jinqiao Zhang, Boyu Yuan, Xianzhou Cai, Luli Ji, Rulin Zhuang, Ziliang Dong
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Nanobiotechnology
Subjects:
Piezoelectric catalysis
Doping-engineered
Exosome inhibition
Tumor treatment
Immunoactivation
Online Access:https://doi.org/10.1186/s12951-025-03564-y
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https://doi.org/10.1186/s12951-025-03564-y

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