RSV Vaccine with Nanoparticle-Based Poly-Sorbitol Transporter (PST) Adjuvant Improves Respiratory Protection Against RSV Through Inducing Both Systemic and Mucosal Humoral Immunity

RSV Vaccine with Nanoparticle-Based Poly-Sorbitol Transporter (PST) Adjuvant Improves Respiratory Protection Against RSV Through Inducing Both Systemic and Mucosal Humoral Immunity

<b>Background/Objectives:</b> Respiratory syncytial virus (RSV) causes symptoms similar to a mild cold for adults, but in case of infants, it causes bronchitis and/or pneumonia, and in some cases, mortality. Mucosal immunity within the respiratory tract includes tissue-resident memory T...

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Main Authors: Seong-Mook Jung, Soo Ji Kim, Young Chae Park, Eun Sang Seo, Cheol Gyun Kim, Taewoo Kim, Sumin Lee, Eunjin Cho, Jun Chang, Cheol-Heui Yun, Byoung-Shik Shim, In Su Cheon, Young Min Son
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Vaccines
Subjects:
respiratory syncytial virus (RSV)
vaccination
adjuvant
poly-sorbitol transporter (PST)
nanovaccine
systemic humoral immune response
Online Access:https://www.mdpi.com/2076-393X/12/12/1354
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https://www.mdpi.com/2076-393X/12/12/1354

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