A novel role for nonactin: interfering with G-quadruplex in RET-driven medullary thyroid cancer
Abstract Background Medullary Thyroid Carcinoma (MTC) is closely associated with mutations in the RET proto-oncogene, placing the activated RET protein at the center of MTC pathogenesis. Existing therapeutic solutions, primarily tyrosine kinase inhibitors such as selpercatinib, vandetanib, and caboz...
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Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-12-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12885-024-13345-9 |
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