Biomineralized engineered Lactococcus lactis-based in situ vaccination enhances antitumor immunity via sequential activation of chemo-immunotherapy

Background Combining chemotherapy with immunotherapy is a promising strategy to enhance in situ immunity by increasing antigen exposure and inflammation in the tumor microenvironment (TME). However, the inconvenience of separate administration and the randomness of delivery can diminish the synergis...

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Bibliographic Details
Main Authors: Yan Wang, Qin Liu, Baorui Liu, Jie Shao, Junmeng Zhu, Rutian Li, Ziqi Chen, Yaohua Ke, Lanqi Cen, Wenmei Rao, Sen Hong, Yanhong Chu, Xiaoping Qian
Format: Article
Language:English
Published: BMJ Publishing Group 2025-08-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/8/e011799.full
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