Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors
Protein SUMOylation is crucial for maintaining the hallmarks of cancer stem cells, including self‐renewal and active pluripotency gene networks. While inhibiting key steps of the SUMOylation cascade has been shown to suppress tumorigenesis, the specific mechanisms of SUMO dependency in cancer have n...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-08-01
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| Series: | Molecular Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/1878-0261.70082 |
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