Integrating TSPO-PET imaging with metabolomics for enhanced prognostic accuracy in multiple sclerosis

Integrating TSPO-PET imaging with metabolomics for enhanced prognostic accuracy in multiple sclerosis

Background Predicting disease progression in multiple sclerosis (MS) remains challenging. PET imaging with 18 kDa translocator protein (TSPO) radioligands can detect microglial and astrocyte activation beyond MRI-visible lesions, which has been shown to be highly predictive of disease progression. W...

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Main Authors: Jens Kuhle, Laura Airas, Daniel C Anthony, David Leppert, Eline Willemse, Fay Probert, Johanna Oechtering, Markus Matilainen, Marcus Sucksdorff, Daniel E Radford-Smith, Abi G Yates, Tereza Kacerova, Marjo Nylund, Aleksandra Maleska Maceski
Format: Article
Language:English
Published: BMJ Publishing Group 2025-04-01
Series:BMJ Neurology Open
Online Access:https://neurologyopen.bmj.com/content/7/1/e001026.full
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https://neurologyopen.bmj.com/content/7/1/e001026.full

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