Development of a personalized digital biomarker of vaccine-associated reactogenicity using wearable sensors and digital twin technology

Abstract Background Effective response to vaccination requires activation of the innate immune system, triggering the synthesis of inflammatory cytokines. The degree of subjective symptoms related to this, referred to as reactogenicity, may predict their eventual immune response. However, the subjec...

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Bibliographic Details
Main Authors: Steven R. Steinhubl, Jadranka Sekaric, Maged Gendy, Huaijian Guo, Matthew P. Ward, Craig J. Goergen, Jennifer L. Anderson, Sarwat Amin, Damen Wilson, Eustache Paramithiotis, Stephan Wegerich
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00840-8
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