Epigenetic control of myogenic identity of human muscle stem cells in Duchenne muscular dystrophy

Epigenetic control of myogenic identity of human muscle stem cells in Duchenne muscular dystrophy

Summary: In Duchenne muscular dystrophy (DMD), muscle stem cells’ (MuSCs) regenerative capacities are overwhelmed leading to fibrosis. Whether MuSCs have intrinsic defects or are disrupted by their environment is unclear. We investigated cell behavior and gene expression of MuSCs from DMD or healthy...

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Main Authors: Jimmy Massenet, Michèle Weiss-Gayet, Hina Bandukwala, Wilhelm Bouchereau, Stéphanie Gobert, Mélanie Magnan, Arnaud Hubas, Patrick Nusbaum, Isabelle Desguerre, Cyril Gitiaux, F. Jeffrey Dilworth, Bénédicte Chazaud
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Epigenetics
Stem cells research
Integrative aspects of cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224025756
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http://www.sciencedirect.com/science/article/pii/S2589004224025756

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