Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) play a central role in early‐stage breast cancer (BC) and are associated with chemoresistance, stemness, and invasion. The objective of this study was two fold: (a) by investigating the predictive value of EMT and TILs...

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Main Authors: Françoise Derouane, Jérôme Ambroise, Cédric vanMarcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Molecular Oncology
Subjects:
early breast cancer
EMT
lymphocytes
neoadjuvant chemotherapy
TILs
Online Access:https://doi.org/10.1002/1878-0261.13813
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https://doi.org/10.1002/1878-0261.13813

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