Green synthesis of Au-Pt bimetallic nanoparticels using Croton caudatus Geisel leaf extract and their biological studies
Metal nanoparticles have a lot of interesting characteristics, and the field of medicinal applications may benefit significantly from them. In this investigation, gold-platinum (Au-Pt) bimetallic nanoparticles were synthesized employing leaf extract from Croton Caudatus Geisel. Utilizing transmissio...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715624006416 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832583090874089472 |
|---|---|
| author | P.Vijaya Kumar K.S. Pushpavalli Baskaran Ganesh Kumar S.Mary Jelastin Kala K.S. Prakash |
| author_facet | P.Vijaya Kumar K.S. Pushpavalli Baskaran Ganesh Kumar S.Mary Jelastin Kala K.S. Prakash |
| author_sort | P.Vijaya Kumar |
| collection | DOAJ |
| description | Metal nanoparticles have a lot of interesting characteristics, and the field of medicinal applications may benefit significantly from them. In this investigation, gold-platinum (Au-Pt) bimetallic nanoparticles were synthesized employing leaf extract from Croton Caudatus Geisel. Utilizing transmission electron microscopy (TEM) examination and powder X-ray diffraction, the size of the synthesized nanoparticles was found to be between 12 and 33 nm. Using Debye Scherrer equation, particle size of the synthesized nanoparticle is determined and also consistent with transmission electron microscopy (TEM) analysis. The materials tend to be rectangular-shaped. This is a single-step, green protocol that does not employ any capping or reducing agents. The bio-active compounds in leaf extract act as reducing/capping/stabilizing agents and also fabricated with surface of the nanoparticles. Since green synthesis is an easy, stable, quick, low-cost, and environmentally friendly process, it opens up new possibilities for the synthesis of nanoparticles. Bimetallic nanoparticle synthesis generally involves mixing two different aqueous metal solutions with a natural reducing agent, like a plant extract. It has been proposed that plant phytochemicals with reducing or antioxidant properties reduce metal ions into metal nanoparticles. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray (EDX) analysis, Fourier-transform infrared (FT-IR) spectroscopy, and ultraviolet (UV) spectroscopy were all utilized to completely characterize the synthesized nanoparticles. It has been found that biological studies exploring in vitro antibacterial, in vitro antifungal, and anti-cancerous activity showed significant implications. In accordance with study results, the synthesized nanomaterials had a strong cytotoxic effect on HeLa cancer cell lines, with an MTT assay IC50 value of 37.17 μg/ml/24 h. |
| format | Article |
| id | doaj-art-5f6c9125fe634f16b59655fcd04ccde0 |
| institution | Kabale University |
| issn | 2211-7156 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj-art-5f6c9125fe634f16b59655fcd04ccde02025-01-29T05:00:39ZengElsevierResults in Chemistry2211-71562025-01-0113101945Green synthesis of Au-Pt bimetallic nanoparticels using Croton caudatus Geisel leaf extract and their biological studiesP.Vijaya Kumar0K.S. Pushpavalli1Baskaran Ganesh Kumar2S.Mary Jelastin Kala3K.S. Prakash4Department of Chemistry, St.Xavier’s College (Autonomous), (Affiliated to Manonmaniam Sundaranar University, Tirunelveli), Palayamkottai 627002, Tamilnadu, IndiaDepartment of Chemistry, St.Xavier’s College (Autonomous), (Affiliated to Manonmaniam Sundaranar University, Tirunelveli), Palayamkottai 627002, Tamilnadu, IndiaDepartment of Chemistry, P.S.R. Arts and College (Affiliated to Madurai Kamaraj University, Madurai), Sivakasi Tamilnadu, India; Department of Science and Humanities, P.S.R. Engineering College (Affiliated to Anna University, Chennai) Sivakasi, Tamilnadu, IndiaDepartment of Chemistry, St.Xavier’s College (Autonomous), (Affiliated to Manonmaniam Sundaranar University, Tirunelveli), Palayamkottai 627002, Tamilnadu, India; Corresponding authors.Department of Chemistry, Bharathidasan Government College for Women (Autonomous) (Affiliated to Pondicherry University, Pondicherry), Muthialpet, Puducherry U.T. PIN 605003, India; Corresponding authors.Metal nanoparticles have a lot of interesting characteristics, and the field of medicinal applications may benefit significantly from them. In this investigation, gold-platinum (Au-Pt) bimetallic nanoparticles were synthesized employing leaf extract from Croton Caudatus Geisel. Utilizing transmission electron microscopy (TEM) examination and powder X-ray diffraction, the size of the synthesized nanoparticles was found to be between 12 and 33 nm. Using Debye Scherrer equation, particle size of the synthesized nanoparticle is determined and also consistent with transmission electron microscopy (TEM) analysis. The materials tend to be rectangular-shaped. This is a single-step, green protocol that does not employ any capping or reducing agents. The bio-active compounds in leaf extract act as reducing/capping/stabilizing agents and also fabricated with surface of the nanoparticles. Since green synthesis is an easy, stable, quick, low-cost, and environmentally friendly process, it opens up new possibilities for the synthesis of nanoparticles. Bimetallic nanoparticle synthesis generally involves mixing two different aqueous metal solutions with a natural reducing agent, like a plant extract. It has been proposed that plant phytochemicals with reducing or antioxidant properties reduce metal ions into metal nanoparticles. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray (EDX) analysis, Fourier-transform infrared (FT-IR) spectroscopy, and ultraviolet (UV) spectroscopy were all utilized to completely characterize the synthesized nanoparticles. It has been found that biological studies exploring in vitro antibacterial, in vitro antifungal, and anti-cancerous activity showed significant implications. In accordance with study results, the synthesized nanomaterials had a strong cytotoxic effect on HeLa cancer cell lines, with an MTT assay IC50 value of 37.17 μg/ml/24 h.http://www.sciencedirect.com/science/article/pii/S2211715624006416BiomaterialsGreen synthesis of NanoparticleCroton Caudatus Geisel Au-Pt metalsX-ray techniques |
| spellingShingle | P.Vijaya Kumar K.S. Pushpavalli Baskaran Ganesh Kumar S.Mary Jelastin Kala K.S. Prakash Green synthesis of Au-Pt bimetallic nanoparticels using Croton caudatus Geisel leaf extract and their biological studies Results in Chemistry Biomaterials Green synthesis of Nanoparticle Croton Caudatus Geisel Au-Pt metals X-ray techniques |
| title | Green synthesis of Au-Pt bimetallic nanoparticels using Croton caudatus Geisel leaf extract and their biological studies |
| title_full | Green synthesis of Au-Pt bimetallic nanoparticels using Croton caudatus Geisel leaf extract and their biological studies |
| title_fullStr | Green synthesis of Au-Pt bimetallic nanoparticels using Croton caudatus Geisel leaf extract and their biological studies |
| title_full_unstemmed | Green synthesis of Au-Pt bimetallic nanoparticels using Croton caudatus Geisel leaf extract and their biological studies |
| title_short | Green synthesis of Au-Pt bimetallic nanoparticels using Croton caudatus Geisel leaf extract and their biological studies |
| title_sort | green synthesis of au pt bimetallic nanoparticels using croton caudatus geisel leaf extract and their biological studies |
| topic | Biomaterials Green synthesis of Nanoparticle Croton Caudatus Geisel Au-Pt metals X-ray techniques |
| url | http://www.sciencedirect.com/science/article/pii/S2211715624006416 |
| work_keys_str_mv | AT pvijayakumar greensynthesisofauptbimetallicnanoparticelsusingcrotoncaudatusgeiselleafextractandtheirbiologicalstudies AT kspushpavalli greensynthesisofauptbimetallicnanoparticelsusingcrotoncaudatusgeiselleafextractandtheirbiologicalstudies AT baskaranganeshkumar greensynthesisofauptbimetallicnanoparticelsusingcrotoncaudatusgeiselleafextractandtheirbiologicalstudies AT smaryjelastinkala greensynthesisofauptbimetallicnanoparticelsusingcrotoncaudatusgeiselleafextractandtheirbiologicalstudies AT ksprakash greensynthesisofauptbimetallicnanoparticelsusingcrotoncaudatusgeiselleafextractandtheirbiologicalstudies |