Prevalence of genetic mutations in Alpha-1 antitrypsin in patients with difficult-to-treat asthma in Colombia
Abstract Background Alpha-1 antitrypsin (AAT) is a medium-sized globular glycoprotein distributed in serum and tissues. In the lungs, it inhibits serine proteases and has anti-inflammatory properties in different types of cells, protecting lung tissue from damage. Mutations in the SERPINA1 gene that...
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| Main Authors: | Abraham Alí-Munive, Jaime Leonardo Chacón, Leidy Prada, Nadia Juliana Proaños, Leslie Vargas, Claudia Diaz-Bossa, Angela Giraldo, John Pedrozo-Pupo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
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| Series: | BMC Pulmonary Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12890-025-03840-5 |
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