DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

Abstract Osteoarthritis (OA) is a widespread musculoskeletal disorder affecting ≈600 million people globally, and small interfering RNA (siRNA) therapy shows potential in targeting OA progression. However, the efficient and targeted delivery of siRNA remains a major challenge due to issues with tiss...

Full description

Saved in:
Bibliographic Details
Main Authors: Qi Lv, Xiang Zhao, Songsong Teng, Xinmeng Jin, Ying Zhou, Yueyang Sun, Hao Pei, Zuoqin Yan, Chunhui Ma
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202503939
Tags: Add Tag
No Tags, Be the first to tag this record!