Unraveling the underlying mechanisms of cancer stem cells in therapeutic resistance for optimizing treatment strategies

Unraveling the underlying mechanisms of cancer stem cells in therapeutic resistance for optimizing treatment strategies

Abstract The success of cancer therapy has been significantly hampered by various mechanisms of therapeutic resistance. Chief among these mechanisms is the presence of clonal heterogeneity within an individual tumor mass. The introduction of the concept of cancer stem cells (CSCs)—a rare and immatur...

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Bibliographic Details
Main Authors: Yunhan Tan, Siyuan Qin, Zhe Zhang, Yongen Liu, Li Zhou, Bowen Li, Edouard C. Nice, Yuanyuan Zhang, Jing Jing
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:MedComm – Oncology
Subjects:
cancer stem cells (CSCs)
combination therapy
CSC‐targeted therapy
drug resistance
Online Access:https://doi.org/10.1002/mog2.70009
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https://doi.org/10.1002/mog2.70009

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