Surveying the repair of ancient DNA from bones via high-throughput sequencing

DNA damage in the form of abasic sites, chemically altered nucleotides, and strand fragmentation is the foremost limitation in obtaining genetic information from many ancient samples. Upon cell death, DNA continues to endure various chemical attacks such as hydrolysis and oxidation, but repair pathw...

Full description

Saved in:
Bibliographic Details
Main Authors: Nathalie Mouttham, Jennifer Klunk, Melanie Kuch, Ron Fourney, Hendrik Poinar
Format: Article
Language:English
Published: Taylor & Francis Group 2015-07-01
Series:BioTechniques
Subjects:
Online Access:https://www.future-science.com/doi/10.2144/000114307
Tags: Add Tag
No Tags, Be the first to tag this record!