Tumor cell-released autophagosomes (TRAPs) induce PD-L1-decorated NETs that suppress T-cell function to promote breast cancer pulmonary metastasis

Background Lung metastasis is the primary cause of breast cancer-related mortality. Neutrophil extracellular traps (NETs) are involved in the progression of breast cancer. However, the mechanism of NET formation is not fully understood. This study posits that tumor cell-released autophagosomes (TRAP...

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Bibliographic Details
Main Authors: Jing Chen, Ning Pan, Li-Xin Wang, Xiaohe Zhou, Chengdong Wu, Xuru Wang, Xiaotong Sun, Bohao Chen, Shiya Zheng, Yiting Wei, Yuyang Wu, Fengjiao Zhu, Jinpeng Chen, Huabiao Chen
Format: Article
Language:English
Published: BMJ Publishing Group 2024-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/6/e009082.full
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