A case report of advanced small intestinal stromal tumor with KIT gene mutation and BRCA2 deletion after multi-line treatments

A case report of advanced small intestinal stromal tumor with KIT gene mutation and BRCA2 deletion after multi-line treatments

This study reports a 40-year-old male with small intestinal stromal tumor (SIST). After initial surgery and adjuvant imatinib, the tumor recurred. The patient then received multiple rounds of treatment with targeted drugs and surgical interventions. Through comprehensive analysis of gene mutation pr...

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Bibliographic Details
Main Authors: Shiyun Cui, Lei Fan, Yu Bai, Xinnan Sun, Yucheng Cai, Jingqi Dai, Ting Wang, Chongqi Sun, Rong Wang, Lianke Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
gastrointestinal stromal tumor
gene mutation
targeted therapy
multidisciplinary treatment
intestinal stromal tumor
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1630699/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1630699/full

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