Orchestrated Cu2+-coordinated tetracycline-porphyrin self-assembly remodels tumor microenvironment for photo-enhanced immuno-chemodynamic therapy

Orchestrated Cu2+-coordinated tetracycline-porphyrin self-assembly remodels tumor microenvironment for photo-enhanced immuno-chemodynamic therapy

Abstract Reactive oxygen species (ROS)-based nanodynamic therapy is emerging as a promising approach for tumor treatment, particularly in eliciting immune responses for tumor immunotherapy. Nevertheless, the complex tumor microenvironment (TME) and the constraints of current sensitizers substantiall...

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Bibliographic Details
Main Authors: Xianbin Sun, Xinyi Wang, Xudong Li, Ya Wang, Ruofei Xu, Xinyi Shen, Ding Tan, Jingjing Liao, Haijun Chen, Yu Gao, Jianping Zheng
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Nanobiotechnology
Subjects:
Orchestrated coordination
Chemodynamic therapy
Cuproptosis
Immunogenic cell death
Tumor microenvironment
Online Access:https://doi.org/10.1186/s12951-025-03486-9
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https://doi.org/10.1186/s12951-025-03486-9

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